HYPERSENSITIVITY AND IMMUNITY REACTIONS AND CLASSIFICATION
نویسندگان
چکیده
منابع مشابه
Drug Hypersensitivity Reactions: Classification and Relationship to T-Cell Activation
The clinical characteristics of drug hypersensitivity reactions are very heterogeneous as drugs can actually elicit all types of immune reactions. The majority of allergic reactions involve either drug-specific IgE or T cells. Their stimulation leads to quite distinct immune responses, which are classified according to Gell and Coombs. Here, an extension of this subclassification, which conside...
متن کاملHypersensitivity reactions
Hypersensitivity refers to undesirable (damaging, discomfort producing and sometimes fatal) reactions produced by the normal immune system. Hypersensitivity reactions require a pre-sensitized (immune) state of the host. Hypersensitivity reactions can be divided into four types: type I, type II, type III and type IV, based on the mechanisms involved and time taken for the reaction. Frequently, a...
متن کاملThe Gell-Coombs classification of hypersensitivity reactions: a re-interpretation.
Gell and Coombs classified hypersensitivity reactions into four 'types'. I suggest that the premise that these reactions represent 'hypersensitivity' manifestations is limiting and that they represent four major strategies that the body uses to combat infectious agents. I further propose that there is a fifth strategy that was not envisioned in the Gell and Coombs classification.
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ژورنال
عنوان ژورنال: Leprosy Review
سال: 1976
ISSN: 0305-7518
DOI: 10.5935/0305-7518.19760027